This observational study among more than 30,000 individuals with pre-existing heart disease and high compliance to statin medications, contributes new evidence to the international debate about the targets of LDL-cholesterol in preventing recurrent cardiac events. This study further supports previous evidence that there are significant protective effects of lowering LDL-C levels to below 100mg/dl, and suggests what a target threshold for long-term statin treatment management may be.
To read the publication and JAMA Internal Medicine editor’s commentary >